In Intento we have two lightweight web applications allowing you to upload different formats of files and translate them via multiple MT engines in a blink of an eye: Intento Web Tools and MT Portal.
Each of these tools supports plain text, HTML, XML or MXLIFF (Memsouce specific format). We plan to roll out support for additional formats on an ongoing basis.
Also, we work with all the formats supported by MS Office and such CAT Tools and TMS integrations as MemoQ, SDL Trados and MateCAT. Please note that different engines might have specific restrictions for certain formats.